Histone lysine methylation in genomic imprinting
نویسندگان
چکیده
منابع مشابه
Histone Lysine Methylation in Diabetic Nephropathy
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In eukaryotic organisms, the replication of the DNA sequence and its organization into chromatin are critical to maintain genome integrity. Chromatin components, such as histone variants and histone post-translational modifications, along with the higher-order chromatin structure, impact several DNA metabolic processes, including replication, transcription, and repair. In this review we focus o...
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Methylation of several lysine residues of histones is a crucial mechanism for relatively long-term regulation of genomic activity. Recent molecular biological studies have demonstrated that the function of histone methylation is more diverse and complex than previously thought. Moreover, studies using newly available genomics techniques, such as exome sequencing, have identified an increasing n...
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ژورنال
عنوان ژورنال: Epigenetics
سال: 2009
ISSN: 1559-2294,1559-2308
DOI: 10.4161/epi.8974